April 15, 2016 – Ferrari stole the spotlight from Mercedes during the second practice session as its two drivers Kimi Raikkonen and Sebastian Vettel topped the times, while the two Mercs settled for P3 and P4. The tyre issues that plagued the first practice session did not reappear.
| Pos | Driver | Car | Time | Gap | Laps |
|---|---|---|---|---|---|
| 1 | Kimi Raikkonen | Ferrari | 1m36.896s | – | 35 |
| 2 | Sebastian Vettel | Ferrari | 1m37.005s | 0.109s | 33 |
| 3 | Nico Rosberg | Mercedes | 1m37.133s | 0.237s | 33 |
| 4 | Lewis Hamilton | Mercedes | 1m37.329s | 0.433s | 33 |
| 5 | Daniel Ricciardo | Red Bull/TAG Heuer | 1m38.143s | 1.247s | 31 |
| 6 | Max Verstappen | Toro Rosso/Ferrari | 1m38.268s | 1.372s | 28 |
| 7 | Nico Hulkenberg | Force India/Mercedes | 1m38.527s | 1.631s | 31 |
| 8 | Carlos Sainz | Toro Rosso/Ferrari | 1m38.542s | 1.646s | 32 |
| 9 | Sergio Perez | Force India/Mercedes | 1m38.569s | 1.673s | 31 |
| 10 | Valtteri Bottas | Williams/Mercedes | 1m38.723s | 1.827s | 34 |
| 11 | Fernando Alonso | McLaren/Honda | 1m38.728s | 1.832s | 31 |
| 12 | Jenson Button | McLaren/Honda | 1m38.828s | 1.932s | 28 |
| 13 | Daniil Kvyat | Red Bull/TAG Heuer | 1m39.178s | 2.282s | 31 |
| 14 | Felipe Massa | Williams/Mercedes | 1m39.214s | 2.318s | 34 |
| 15 | Jolyon Palmer | Renault | 1m39.774s | 2.878s | 32 |
| 16 | Romain Grosjean | Haas/Ferrari | 1m39.890s | 2.994s | 22 |
| 17 | Pascal Wehrlein | Manor/Mercedes | 1m39.941s | 3.045s | 36 |
| 18 | Marcus Ericsson | Sauber/Ferrari | 1m39.979s | 3.083s | 35 |
| 19 | Rio Haryanto | Manor/Mercedes | 1m40.550s | 3.654s | 33 |
| 20 | Felipe Nasr | Sauber/Ferrari | 1m41.066s | 4.170s | 32 |
| 21 | Esteban Gutierrez | Haas/Ferrari | 1m42.954s | 6.058s | 4 |
