May 13, 2016 – Sebastian Vettel led team mate Kimi Raikkonen as Ferrari made full use of their soft tyres to top the timesheet in first practice at the Circuit de Barcelona-Catalunya on Friday morning.
| Pos | Driver | Car | Time | Gap | Laps |
|---|---|---|---|---|---|
| 1 | Sebastian Vettel | Ferrari | 1m23.951s | – | 22 |
| 2 | Kimi Raikkonen | Ferrari | 1m24.089s | 0.138s | 18 |
| 3 | Nico Rosberg | Mercedes | 1m24.454s | 0.503s | 34 |
| 4 | Lewis Hamilton | Mercedes | 1m24.611s | 0.660s | 33 |
| 5 | Daniel Ricciardo | Red Bull/Renault | 1m25.416s | 1.465s | 25 |
| 6 | Max Verstappen | Red Bull/Renault | 1m25.585s | 1.634s | 29 |
| 7 | Valtteri Bottas | Williams/Mercedes | 1m25.672s | 1.721s | 36 |
| 8 | Carlos Sainz | Toro Rosso/Ferrari | 1m26.078s | 2.127s | 19 |
| 9 | Felipe Massa | Williams/Mercedes | 1m26.186s | 2.235s | 32 |
| 10 | Fernando Alonso | McLaren/Honda | 1m26.243s | 2.292s | 18 |
| 11 | Kevin Magnussen | Renault | 1m26.576s | 2.625s | 30 |
| 12 | Daniil Kvyat | Toro Rosso/Ferrari | 1m26.583s | 2.632s | 21 |
| 13 | Nico Hulkenberg | Force India/Mercedes | 1m26.938s | 2.987s | 27 |
| 14 | Sergio Perez | Force India/Mercedes | 1m27.064s | 3.113s | 9 |
| 15 | Felipe Nasr | Sauber/Ferrari | 1m27.253s | 3.302s | 27 |
| 16 | Romain Grosjean | Haas/Ferrari | 1m27.258s | 3.307s | 17 |
| 17 | Esteban Gutierrez | Haas/Ferrari | 1m27.283s | 3.332s | 18 |
| 18 | Marcus Ericsson | Sauber/Ferrari | 1m27.392s | 3.441s | 24 |
| 19 | Jenson Button | McLaren/Honda | 1m27.610s | 3.659s | 19 |
| 20 | Pascal Wehrlein | Manor/Mercedes | 1m28.084s | 4.133s | 29 |
| 21 | Rio Haryanto | Manor/Mercedes | 1m29.052s | 5.101s | 34 |
| 22 | Esteban Ocon | Renault | – | – | 6 |
